Macrolane VRF 20 (10ml) is the lower-viscosity formulation in Q-Med’s Macrolane range, built on the same proven NASHA™ (Non-Animal Stabilised Hyaluronic Acid) technology as VRF 30, but engineered for shallower injection planes and more precise, targeted work. Where VRF 30 delivers deep volumetric foundation, VRF 20 excels at the finishing layer, smoothing surface irregularities, correcting fine contour defects, and achieving natural-looking refinement that bulk volume alone cannot provide.
The 10ml format makes VRF 20 particularly well suited to smaller, localised treatment areas, targeted scar correction, and use as a complementary product alongside VRF 30 in layered treatment protocols.
What Is Macrolane VRF 20 (10ml) Used For?
Macrolane VRF 20 is indicated for non-surgical body contouring, surface smoothing and volume correction, including:
- Post-liposuction irregularities, correcting shallow contour deformities and surface depressions that remain after surgical procedures
- Scar correction, filling dent-shaped or depressed scars, particularly those with a more superficial profile
- Surface contouring, smoothing skin irregularities and refining body contours in smaller or more delicate areas
- Layered protocols, used as a superficial finishing layer following deep injection of VRF 30 to achieve a smooth, natural surface result
Note on breast use: Q-Med discontinued the breast augmentation indication for Macrolane. Macrolane VRF 20 is not recommended or indicated for breast tissue augmentation.
VRF 20 vs VRF 30, Choosing the Right Formulation
Understanding the difference between the two Macrolane formulations is essential for optimal results:
Macrolane VRF 20 Macrolane VRF 30
Viscosity Lower Higher
Primary role Surface smoothing, finishing layer, targeted correction Deep volume restoration, primary augmentation
Injection plane Superficial subcutaneous / deep dermis Deep subcutaneous, above muscle
Volume 10ml, targeted use 10ml or 20ml, larger area coverage
Best combined with VRF 30 as a base layer VRF 20 as a surface finishing layer
For many practitioners, the ideal protocol combines VRF 30 as the deep structural base and VRF 20 for precision surface work, achieving both volume and natural-looking smoothness in a single treatment session.
Key Product Details
Specification Detail
Active Ingredient Stabilised Hyaluronic Acid (NASHA™), 20mg/ml
Volume 10ml per syringe
Formulation Non-animal origin; biodegradable
Injection Plane Superficial subcutaneous / deep dermis
Duration of Effect Up to 12–18 months
Manufacturer Q-Med / Galderma
Animal Derivatives None
⚠️ For use by qualified and specifically trained medical practitioners only. Macrolane must not be used on the face. Always refer to full product guidelines before use.
Why Practitioners Choose Macrolane VRF 20 (10ml)
✅ Precision in smaller areas, the 10ml format is ideal for targeted work, top-up treatments, and areas requiring less volume
✅ Superficial injection capability, lower viscosity than VRF 30 allows injection into shallower tissue planes without risk of visible nodularity
✅ Seamless layering, pairs perfectly with VRF 30 to create comprehensive, full-depth contouring results
✅ Biodegradable and reversible, naturally absorbed over time; can be dissolved with hyaluronidase if required
✅ No animal derivatives, pure synthetic NASHA™ HA with zero risk of animal-origin contamination
✅ Minimal downtime, patients typically return to normal activities within 24–48 hours
Important Safety Information
Macrolane VRF 20 is contraindicated in patients who:
Have known hypersensitivity to hyaluronic acid or any excipients
Have an autoimmune disease
Have an active infection or skin condition at the proposed treatment site
Are pregnant or breastfeeding
Common side effects include temporary swelling, bruising, tenderness, and mild discomfort at the injection site. Macrolane must not be injected into the face, blood vessels, muscles, tendons, ligaments, or bone.
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